The Coming of Age of Microfluidic Biochips: Connection Biochemistry to Electronic Design Automation
|Title:||The Coming of Age of Microfluidic Biochips: Connection Biochemistry to Electronic Design Automation|
|Date:||May 15, 2020 (Friday)|
|Time:||9:30 am - 11:00 am|
|Speaker:|| Prof. Tsung-yi HO
Department of Computer Science
National Tsing Hua University
Advances in microfluidic technologies have led to the emergence of biochip devices for automating laboratory procedures in biochemistry and molecular biology. Corresponding systems are revolutionizing a diverse range of applications, e.g., point-of-care clinical diagnostics, drug discovery, and DNA sequencing–with an increasing market. However, continued growth (and larger revenues resulting from technology adoption by pharmaceutical and healthcare companies) depends on advances in chip integration and design-automation tools. Thus, there is a need to deliver the same level of design automation support to the biochip designer that the semiconductor industry now takes for granted. In particular, the design of efficient design automation algorithms for implementing biochemistry protocols to ensure that biochips are as versatile as the macro-labs that they are intended to replace. This talk will first describe technology platforms for accomplishing “biochemistry on a chip”, and introduce the audience to both the droplet-based "digital" microfluidics based on electrowetting actuation and flow-based “continuous” microfluidics based on microvalve technology. Next, system-level synthesis includes operation scheduling and resource binding algorithms, physical-level synthesis includes placement and routing optimizations, and control synthesis and sensor feedback-based cyberphysical adaptation will be presented. In this way, the audience will see how a “biochip compiler” can translate protocol descriptions provided by an end user (e.g., a chemist or a nurse at a doctor’s clinic) to a set of optimized and executable fluidic instructions that will run on the underlying microfluidic platform. Finally, recent advances in open-source microfluidic ecosystem will be covered.
Tsung-Yi Ho received his Ph.D. in Electrical Engineering from National Taiwan University in 2005. He is a Professor with the Department of Computer Science of National Tsing Hua University, Hsinchu, Taiwan. His research interests include several areas of computing and emerging technologies, especially in design automation of microfluidic biochips. He has been the recipient of the Invitational Fellowship of the Japan Society for the Promotion of Science (JSPS), the Humboldt Research Fellowship by the Alexander von Humboldt Foundation, the Hans Fischer Fellowship by the Institute of Advanced Study of the Technische Universität München, and the International Visiting Research Scholarship by the Peter Wall Institute of Advanced Study of the University of British Columbia. He was a recipient of the Best Paper Awards at the VLSI Test Symposium (VTS) in 2013 and IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems in 2015. He served as a Distinguished Visitor of the IEEE Computer Society for 2013-2015, a Distinguished Lecturer of the IEEE Circuits and Systems Society for 2016-2017, the Chair of the IEEE Computer Society Tainan Chapter for 2013-2015, and the Chair of the ACM SIGDA Taiwan Chapter for 2014-2015. Currently, he serves as the Program Director of both EDA and AI Research Programs of Ministry of Science and Technology in Taiwan, the VP Technical Activities of IEEE CEDA, an ACM Distinguished Speaker, and an Associate Editor of the ACM Journal on Emerging Technologies in Computing Systems, ACM Transactions on Design Automation of Electronic Systems, ACM Transactions on Embedded Computing Systems, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, and IEEE Transactions on Very Large Scale Integration Systems, a Guest Editor of IEEE Design & Test of Computers, and the Technical Program Committees of major conferences, including DAC, ICCAD, DATE, ASP-DAC, ISPD, ICCD, etc. He is a Distinguished Member of ACM.
Enquiries: Miss Caroline Tai at Tel. 3943 8440
For more information, please refer to http://www.cse.cuhk.edu.hk/en/events