| Title: | The Whole Genome Alignment Problem |
| Date: |
January 13, 2006 (Friday)
|
| Time: |
1:30 p.m. - 2:30 p.m.
|
| Venue: |
Room 121, 1/F, Ho Sin-hang Engineering Building,
The Chinese University of Hong Kong, Shatin, N.T. |
| Speaker: |
Dr. Yiu Siu Ming
Research Assistant Professor Department of Computer Science The University of Hong Kong |
From a biological point of view, the whole genome alignment problem can be described as follows. In a genomic sequence, some regions of it are believed to be functional units (e.g. genes). Given two genomic sequences, the whole genome alignment problem is to locate the conserved regions (the regions that have similar functions) between the sequences. In other words, the problem is to find a mapping between the conserved regions in the two genomes. In this talk, we first will give a brief introduction to some necessary biological concepts for the audience to understand the whole genome alignment problem. Then, based on some data analysis and biological observations, we will show how we formulate some computational problems to tackle this biological problem. Experimental results will be presented to show that our solutions give better results than the existing approaches. Future directions and some issues in conducting bioinformatics research will also be discussed.
BIOGRAPHY:
Dr Yiu is currently a Research Assistant Professor in the Department of Computer Science of the University of Hong Kong. His current research interest is in the area of Bioinformatics. He was one of the two recipients of the Best Teacher Award of the Faculty of Engineering in 2004-2005 and has been selected four times for the annual Teaching Excellence Award of the Department of the Computer Science since 2000. He is also the programme coordinator of the BSc degree in Bioinformatics which is jointly offered by the Department of Computer Science and the Biochemistry Department.
Enquiries: Miss Temmy So at tel 2609 8444
For more information, please refer to http://www.cse.cuhk.edu.hk/seminar